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KMID : 0191120220370500347
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Journal of Korean Medical Science
2022 Volume.37 No. 50 p.347 ~ p.347
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Correlation Between Third Dose of COVID-19 Vaccines and Regional Case Fatality Rates During the Omicron Wave in Korea
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Jang Young-Ook
Kim In-Joong
Moon Sung-Sil
Kim Sun-Bean
Lee Jacob
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Abstract
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This study seeks to find the correlation between case fatality rates (CFRs) and third-dose vaccination coverage in 244 counties (si/gun/gu) of South Korea during the omicron variant wave. Multivariate regression analyses report that the higher third-dose vaccination rates were correlated with lower regional CFRs, when controlling for age structure. If the third-dose vaccination rate of a county is higher by 10%, it would have a CFR lower by 0.05% (95% confidence interval, 0.03?0.08%). As the number of cumulative confirmed cases in South Korea was 16,353,495 as of April 20, 2022, a lower CFR by 0.03?0.08% is equivalent to 4,394?12,448 lives (8.6?24.4 per 100,000) spared. County-specific characteristics, such as age structure, intensive care unit availability, and the level of non-pharmaceutical interventions may also affect the extent of this correlation. The conclusion implicates the potential role of coronavirus disease 2019 vaccines in reducing the pressure on the regional healthcare capacity.
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KEYWORD
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Coronavirus, Vaccines, Mortality, Omicron, Korea
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